Anxiety

Clinic

• Anxiety is an entity which contain sign/symptoms such as Uneasiness / Worry/ Palpitation / Hyper hydrosis / Mouth dryness
• Its underlying mechanism is Sympathetic hyperactivity.

Anxiety vs. Fear

• Both are entities, differentiating from their qualities as below.

Four main domains	Fear	Anxiety
Duration of emotional experience	Short	Long
Temporal focus	Present	Futute
Specificity of the threat	Specific	Diffuse
Motivated direction	Escape	Additional associated cognitive activity

Neuroanatomy

• Amygdala (which regulates emotions like anxiety and fear, stimulating the HPA axis and sympathetic nervous system). People who have anxiety tend to show high activity in response to emotional stimuli in the amygdala. Some writers believe that excessive anxiety can lead to an overpotentiation of the limbic system (which includes the amygdala and nucleus accumbens), giving increased future anxiety, but this does not appear to have been proven.
• Hippocampus (which is implicated in emotional memory along with the amygdala)

• Research upon adolescents who as infants had been highly apprehensive, vigilant, and fearful finds that their nucleus accumbens is more sensitive than that in other people when deciding to make an action that determined whether they received a reward. This suggests a link between circuits responsible for fear and also reward in anxious people. As researchers note, "a sense of 'responsibility', or self-agency, in a context of uncertainty (probabilistic outcomes) drives the neural system underlying appetitive motivation (i.e., nucleus accumbens) more strongly in temperamentally inhibited than noninhibited adolescents".

The gut-brain axis

• The microbes of the gut can connect with the brain to affect anxiety. Gut microbes such as Bifidobacterium and Bacillus produce GABA and dopamine, respectively.
• Another key pathway is HPA axis. The microbes can control the levels of cytokines in the body, and altering cytokine levels creates direct effects on areas of the brain such as the hypothalamus, the area that triggers HPA axis activity.
• HPA axis regulates production of cortisol. When HPA activity spikes, cortisol levels increase, processing and reducing anxiety in stressful situations.

Remedies

Remedies	Mind /Physical /General Characters		Fear of	Disease
Acon	Mind His thoughts are coming from stomach Great Anxiety / Excitement /Hasty Tendency to start at everything Intense, sudden General / Physical Characters Dry skin, dry mouth, and fast heartbeat Extremely restless: Tosses about in agony, Must change his position often.		Music is unbearable Future Going out Crowd Crossing street	Panic Fear PTSD
Arg-n	Mind Anxiety due to uncertainty Always in Hurry. Time passes too slowly Sad/ Melancholic Forgetfulness / Dull It could be accompanied with digestive disturbance, like diarrhea and . Anxiety makes the patient to walk fast Anxiety due to anticipation Patient is always in hurry, . Impulsive/ Impulse to jump, when in a high place. General / Physical Characters Diarrhea Sweets cravings but agg		Cannot face the strangers. Looking at high places Fear of crossing corners of street, Fear of death	Claustrophobia Hypochondriasis
Ars	Mind Fastidious/ Suspicious Control their anxiety to prevent being criticized by others. Sad/ Hopeless of recovery Suicidal tendencies / Weary of life/ Impulse to suicide General / Physical Characters Often feel cold Weak: Always moving from one place to another, Even physically too weak to move, they want to be moved.		Loneliness, Darkness Being imperfect About money As if he will die soon Incurable disease.	OCD
Calc	Evening anxiety + Restlessness + Palpitation + Mental weakness (Inability to prolonged mental exertion, difficult thinking, Weak memory, Confusion, Misplacing of words, Indolence). Irritable/ Obstinate/ Sad/ Inclined to weep Prolonged worry or anxiety, prolonged application to business, from excitement of the emotions. Horrible dreams, startled at every noise.		Breaking out of any safe routine/ Insecurity in changing Routines / plans (Like Ars Difficulty in “going with the flow.”) Insanity/ Loss of reason Death/ Consumption Misfortune Alone
Gels	Mind Timid/ Feelings of inadequacy They often desire solitude and avoid insistent pressure from other people. General / Physical Characters Shaky, Vulnerable to fainting		Anxiety due to fright, fear, exciting news, Stage fright: Examination or interview etc.	Agoraphobia: avoid crowds or public speaking
Ign	Mind Very sensitive Anxiety from Grief or Loss or Mental shock Mood swings: Moving from laughter to tears, Alteration of opposite mental states. Depression, Absent-minded, aversion to company / Weeps and broods in solitude Hysterical from disappointment; patient weeps, laughs, shrieks, jerks and twitches and may go in to convulsions or faint. / Unable to control her Emotions /Excitement.			Mood swings Depression Hysteria
Kali-ars	Mind Fear of heart attacks Health-based anxiety include hypochondria, Excessive grooming Racing thoughts and difficulty sleeping General / Physical Characters Feeling cold		Fear of death or dying Fear of heart attacks	Panic attacks Hypochondriasis
Kali-p	Mind Anxiety from having too much to do or increased ambitions Vulnerable to stress or becoming overwhelmed. General / Physical Characters Physical complication of anxiety
Phos	Difficult concentration when anxious: Scattered / Difficult time focusing or getting things done Social people with anxiety		Anxiety of being approved in social circles or from romantic partners
Sul	Forgetful/ Confused / Absent minded Aversion to mental, as well as physical efforts. Overambitious, day-dreams, boaster. Irritable, impatient of others, selfish, easily excited and offended. Always in dreams, delusions, thinks rags to be beautiful things. He is a ragged philosopher, very unclean, does not care for neatness, he thinks there is no need of cleanliness. Suspicious and mentally depressed. General / Physical Characters Anxiety with Fainting spells, Profuse sweating, / Agg in the morning. Mentally lazy, always tired, occasionally restlessness and hasty. Aversion to bathing.			Depression
Borx	Fear of falling Fidgetiness and nervousness. Anxious about trifles, Easily frightened by slightest noise Children wake suddenly, screaming and grasping sides of cradle without apparent cause.	Anxiety agg by upward or downward motion, going in elevator Worse till 11 p.m.
Lyc	Lack self-confidence (Similar to Gels, Sil)		Fear of speaking in public but they hide it well by talking loudly or loquacity	Stage fright:
Puls	Childlike anxiety They need lots of reassurance and support from others to feel better.
Sil	Lack self-confidence (Similar to Gels, Lyc) Fear of being the center of attention They tend to become workaholics to soothe their fears.		Fear experiencing new things	Stage fright
Stram	Dark thoughts while awake Their imaginations tend to worsen their anxiety Scared by thoughts of monsters or mysterious figures		Fear of the dark Fear of being alone	Night terrors Nightmares Bed wetting Stammering speech
Anac	Dullness / Sluggishness of mind /Memory impaired / Sudden loss of memory / Absent mindedness Suspicious about everything around him Lack of confidence in himself and others Very easily offended Irresistible desire to curse and swear,Abusive Aversion to work, indolence Thinks he is possessed of two wills, one commanding to do what other forbids Hallucinations that a demon sits on one shoulder and an angel on the other Feels he is double, Mind -Body separation. General / Physical Characters Anxiety better after eating Anxious while walking, as if someone is pursuing him. All complaints are worse from mental exertion.			Schizophrenia
Bry	Mind Mind is hazy and confused. The patient dozes frequently, while his eyes are closed, he sees people who are not in the room. Mild type of delirium first during sleep, and later on during waking hours. He wants to go home as he thinks he is away from home He wants something but do not know what he wants, desires things which cannot be had, which are refused when offered.		Anxious about business, even when seriously ill Talks incoherently, about Business affairs/ Events of recent happening,

Borx

• Anxiety aggravated by upward or downward motion, going in elevator
• Worse till 11 p.m.
• Fear of falling when rocking, dancing, singing, going downstairs, or going rapidly down to the hill.
• Fidgetiness and nervousness.
• Anxious about trifles
• Excessive nervous, easily frightened by slightest noise or an unusual sharp sound, a cough, a sneeze, cry, lighting a match etc.
• Patient becomes nauseated and excitable after mental exertion and in anxiety.
• Children wake suddenly, screaming and grasping sides of cradle without apparent cause.

Caust

• Full of apprehension; patient is melancholic, lachrymose, hopeless, and foreboding.
• Prone to fits of anger, startled easily, the least things make the child cry who is peevish.
• Forgetful, taciturn, and extremely restless, especially at night.
• Always anticipating some dreadful events,
• She lacks mental balance, hysterical women who have lost all control of herself, esp at night.
• Intensely sympathetic for suffering of others, ailments are worse when thinking about them.
• Mental symptoms that come on from suppression from skin eruptions.

Small Remedies

Cact: Very anxious and restless and screams in pain.