EBV, Epstein Barr Virus: Difference between revisions

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* EBV is one of the nine known human [[Herpes viruses|herpesvirus types]] in the herpes family
* EBV is one of the nine known human [[Herpes viruses|herpesvirus types]] in the herpes family
* It is one of the most common viruses in humans.
* It is one of the most common [[viral miasms]] in human.
* It is best known as the cause of infectious mononucleosis ("mono" or "glandular fever").  
* It is best known as the cause of [[Mononucleosis|infectious mononucleosis.]]
 


=== Related disease ===
=== Related disease ===
* Lymphoproliferative diseases such as
** Burkitt lymphoma
** Hemophagocytic lymphohistiocytosis
** Hodgkin's lymphoma
* Non-lymphoid malignancies such as  
* Non-lymphoid malignancies such as  
** Gastric cancer
** Gastric [[cancer]]
** '''''External throat:''''' Nasopharyngeal carcinoma
** '''''External throat:''''' Nasopharyngeal carcinoma
**''Jaw tumor''
**''Jaw tumor''
**''Pericardial tumor''
**''Pericardial tumor''
**''Breast; cancer''
**''Breast; [[cancer]]''
**''Pleural tumor''
**''Pleural tumor''
**''Liver; cancer''
**''Liver [[cancer]]''
* Conditions associated with HIV such as  
* Conditions associated with [[HIV, Human immunodeficiency virus|HIV]] such as  
** Oral Hairy leukoplakia : White or red discoloration of tongue''. Tongue; white lesion on the lateral''.
** Oral Hairy [[leukoplakia]] : White or red discoloration of tongue''. Tongue; white lesion on the lateral''.
** CNS lymphomas
** CNS lymphomas
* Autoimune disorders
* Autoimmune disorders
** Alice in Wonderland syndrome
** [[MS, Multiple Sclerosis|MS]]
** Acute [[Cerebellar ataxia miasms|cerebellar ataxia]]
** [[Dermatomyositis]]
** [[SLE, Systemic lupus erythematosus|SLE]]
** Rheumatoid arthritis
** [[Sjogren's syndrome|Sjögren's syndrome]]
** [[MS, Multiple Sclerosis|MS]]  


*
* [[Gianotti Crosti syndrome|Gianotti–Crosti syndrome]]   
* [[Gianotti Crosti syndrome|Gianotti–Crosti syndrome]]   
* Erythema multiforme
* Erythema multiforme
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''Infectious mononucleosis''
==== ''Infectious [[mononucleosis]]'' ====
 
* [[Fatigue]], fever, inflamed throat, swollen lymph nodes in the neck, enlarged spleen, swollen liver, or rash.  
* Fatigue, fever, inflamed throat, swollen lymph nodes in the neck, enlarged spleen, swollen liver, or rash.  
* [[CFS, Chronic Fatigue syndrome|Chronic Fatigue Syndrome]]  
* [[Chronic fatigue syndrome (CFS)|Chronic Fatigue Syndrome]]  


* Severe hypersensitivity, Mosquito bite allergy reactions
* Severe [[hypersensitivity]], Mosquito bite allergy reactions
* Mucocutaneous ulcers
* Mucocutaneous ulcers
* Hydroa vacciniforme
* Hydroa vacciniforme




=== Entities ===
{| class="wikitable"
 
|+
* '''Lymphadenopathy: Axillary, Submandibular, Symmetrical Cervical, Inguinal , Back Adenopathy'''
![[Entities list|Entities]]
 
!Sign / Symptoms
* ''Periorbital edema''  
!Related disease
 
!
* ''Uveitis''  
!
* ''Optic neuritis''
|-
|''[[Uveitis]]''
|
|
|
|
|-
|''[[Optic neuritis]]''
|
|
|
|
|-
|
* '''[[Pharyngitis]]'''
* '''[[Tonsillitis]]'''
|
* '''Sore throat'''
* '''Erythematous'''
* '''Swelling of tonsils'''
* '''xudation'''
* '''Tonsils meet at the midline'''
* Ulcers.
|
|
|
|-
|
* ''Interstitial [[nephritis]]''
|
* '''Hematuria; microscopic.'''
* '''Increased Sediment Urine'''
* '''Proteinuria'''
|''Acute Renal failure''
|
|
|-
|
* ''[[Pericarditis]]''
* ''[[Myocarditis]]''
|Palpitation
|
|
|
|-
|
* ''[[Pneumonia]]''
* ''I[[Interstitial pneumonitis|nterstitial pneumonitis]]'':
|''[[Cough remedies|Cough]]''
|
|
|
|-
|''[[Arthritis]]''
|
|
*[[SLE, Systemic lupus erythematosus|SLE]]
* [[Arthritis|Rheumatoid arthritis]]
* [[Sjogren's syndrome|Sjögren's syndrome]]
|
|
|-
|'''[[Hepatitis]]'''
|
* ''Hepatomegaly''
* '''''Tenderness / fullness of Right upper quadrant of Abdomen'''''
* '''''Elevated right hemidiaphragm'''''
* ''Yellow face''
* ''Nausea. Vomiting.''
* LFT rising
|
* ''Fulminant'' '''[[Hepatitis]]'''
* ''Persistent'' '''[[Hepatitis]]'''
* '''''Hepatic failure'''''
* ''[[Cirrhosis remedies|Cirrhosis]]''
|
|
|-
|
|
* '''[[Splenomegaly miasms|Splenomegaly]]'''
* ''Discomfort''
* ''Pain''; ''left upper quadrant ext to left scapular region''
* ''Abrupt'' ''Pain''
* '''[[Bleeding, hemorrhagic remedies|Petechiae]] esp on Palate`'''
|
* ''Splenic subcapsular bleeding''
* ''Splenic subcapsular hematoma''
* ''Splenic rupture''
|
|
|-
|
|
* ''Eruptions''
* ''Erythema multiforme - like, macular''
* ''Scarlatiniform''
|
|
|
|-
|[[Lymphadenitis]]
|
* '''Lymphadenopathy'''
* '''Axillary, Submandibular,'''
* '''Symmetrical Cervical, Inguinal , Back Adenopathy'''
|
* [[Mononucleosis|Infectious mononucleosis]]
* Lymphoproliferative diseases such as
** Burkitt lymphoma
** Hemophagocytic lymphohistiocytosis
** Hodgkin's [[Lymphoma remedies|lymphoma]]
|
|
|-
|
|
* ''[[Urticaria]]''
* '''Ampicillin-induced Rash'''
|
|
|
|-
|[[Encephalitis]]
|
* Fever (18%),
* [[Headache]] (66%)
* [[Seizure|Seizures]] (48%)
* EEG signs (57%)
* Abnormal MRI findings (71%): Basal ganglia and the striatal body, esp in the putamen and caudate nucleus <ref>Hashemian S, Ashrafzadeh F, Akhondian J, Beiraghi Toosi M. Epstein-barr virus encephalitis: a case report. Iran J Child Neurol. 2015 Winter;9(1):107-10. PMID: 25767548; PMCID: PMC4322508.</ref>
|
* Acute childhood encephalitis
* Alice in Wonderland syndrome
|
|
|-
|[[Aseptic meningitis remedies|Aseptic meningitis]]:
|'''Retro-orbital [[Headache]]'''
|
|
|
|-
|
|
* [[Transverse myelitis]]
* ''[[Brachial plexus neuropathy]]''
|[[GBS, Guillian Barre syndrome|Guillain-Barre syndrome]]
|
|
|-
|[[Bel's palsy|Bel’s palsy]]
|
|
|
|
|-
|[[Cerebellar ataxia]]
|
|Acute [[cerebellar ataxia]]
|
|
|-
|
|
|[[Dermatomyositis]]
|
|}
* ''Periorbital edema''


* '''Nose''' Catarrh.   
* '''Nose''' Catarrh.   


* '''Mouth''' Offensive odor. '''Palatal enanthem; ; at the junction of soft and hard palate.''' Lip ulcers. Cracked tongue.
* '''Mouth''' Offensive odor. '''Palatal enanthem at the junction of soft and hard palate.''' Lip ulcers. Cracked tongue.


* '''Pharyngitis, Tonsillitis: Sore throat. Erythematous,  Swelling of tonsils. Exudation. Tonsils meet at the midline.''' Ulcers.
* Constipation. [[Diarrhea]].  
* '''Hepatitis:''' ''Fulminant, persistent''. '''''Hepatic failure.''' Cirrhosis. Hepatomegaly, '''Tenderness of left upper quadrant, Sensation of fullness in Abdomen, Elevated left hemidiaphragm. .'''  Yellow face, Nausea. Vomiting.''
* [[Hemorrhoid|Hemorrhoids]]: '''Rectum Pain'''
* '''Splenomegaly,''' ''Splenic subcapsular bleeding. Splenic subcapsular hematoma''. ''Splenic rupture''. ''Discomfort''. ''Pain''; ''left upper quadrant ext to left scapular region; abrupt''.
* Acrid [[PID, Pelvic inflammatory disease|Leukorrhea]]
 
* Trembling of hands. ''[[Hemiplegia miasms|Hemiplegia]]''
* Constipation. Diarrhea.  
* [[Wound ulcer remedies|Ulcers]]
* Hemorrhoids: '''Rectum Pain'''
 
* ''Interstitial nephritis''. ''Acute Renal failure'': '''Hematuria; microscopic. Sediment Urine. Proteinuria'''
* ''Pericarditis''.
* ''Myocarditis'': Palpitation
* ''Pneumonia; interstitial, Pneumonitis; interstitial'': ''Cough''
* Acrid Leukorrhea
* ''Arthritis''.
* Trembling of hands. ''Hemiplegia''
* ''Eruptions; erythema multiforme - like, macular, , scarlatiniform,''
 
* ''Urticaria''. ''' '''
* '''Ampicillin-induced Rash.'''
* Ulcers:
* '''Petechiae esp on Palate'''
* '''Fever: afternoon, low grade,''' ''prolonged''.
* '''Fever: afternoon, low grade,''' ''prolonged''.


 
=== Remedies ===
=== Neurological manifestations ===
 
* Encephalitis: Acute childhood encephalitis and remains the most common agent mimicking herpes simplex virus encephalitis, Fever (18%), Headache (66%). Seizures (48%), EEG signs (57%); Abnormal MRI findings (71%)
 
* Aseptic meningitis: '''Retro-orbital Headache;'''
* Transverse myelitis: ''Brachial plexus neuropathy.''
* Guillain-Barre syndrome
* Bell’s palsy
* Cerebellar ataxia
* MRI: Basal ganglia and the striatal body, especially in the putamen and caudate nucleus <ref>Hashemian S, Ashrafzadeh F, Akhondian J, Beiraghi Toosi M. Epstein-barr virus encephalitis: a case report. Iran J Child Neurol. 2015 Winter;9(1):107-10. PMID: 25767548; PMCID: PMC4322508.</ref>

Revision as of 03:23, 31 August 2023

Clinic


Related disease

  • Non-lymphoid malignancies such as
    • Gastric cancer
    • External throat: Nasopharyngeal carcinoma
    • Jaw tumor
    • Pericardial tumor
    • Breast; cancer
    • Pleural tumor
    • Liver cancer
  • Conditions associated with HIV such as
    • Oral Hairy leukoplakia : White or red discoloration of tongue. Tongue; white lesion on the lateral.
    • CNS lymphomas
  • Autoimmune disorders


Infectious mononucleosis

  • Severe hypersensitivity, Mosquito bite allergy reactions
  • Mucocutaneous ulcers
  • Hydroa vacciniforme


Entities Sign / Symptoms Related disease
Uveitis
Optic neuritis
  • Sore throat
  • Erythematous
  • Swelling of tonsils
  • xudation
  • Tonsils meet at the midline
  • Ulcers.
  • Hematuria; microscopic.
  • Increased Sediment Urine
  • Proteinuria
 Acute Renal failure
Palpitation
Cough
Arthritis
Hepatitis
  • Hepatomegaly
  • Tenderness / fullness of Right upper quadrant of Abdomen
  • Elevated right hemidiaphragm
  • Yellow face
  • Nausea. Vomiting.
  • LFT rising
  • Splenomegaly
  • Discomfort
  • Pain; left upper quadrant ext to left scapular region
  • Abrupt Pain
  • Petechiae esp on Palate`
  • Splenic subcapsular bleeding
  • Splenic subcapsular hematoma
  • Splenic rupture
  • Eruptions
  • Erythema multiforme - like, macular
  • Scarlatiniform
Lymphadenitis
  • Lymphadenopathy
  • Axillary, Submandibular,
  • Symmetrical Cervical, Inguinal , Back Adenopathy
Encephalitis
  • Fever (18%),
  • Headache (66%)
  • Seizures (48%)
  • EEG signs (57%)
  • Abnormal MRI findings (71%): Basal ganglia and the striatal body, esp in the putamen and caudate nucleus [1]
  • Acute childhood encephalitis
  • Alice in Wonderland syndrome
Aseptic meningitis: Retro-orbital Headache
Guillain-Barre syndrome
Bel’s palsy
Cerebellar ataxia Acute cerebellar ataxia
Dermatomyositis
  • Periorbital edema
  • Nose Catarrh.
  • Mouth Offensive odor. Palatal enanthem at the junction of soft and hard palate. Lip ulcers. Cracked tongue.

Remedies

  1. ↑ Hashemian S, Ashrafzadeh F, Akhondian J, Beiraghi Toosi M. Epstein-barr virus encephalitis: a case report. Iran J Child Neurol. 2015 Winter;9(1):107-10. PMID: 25767548; PMCID: PMC4322508.
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