CNS Disease

MS

ALS (Motor Neuron Disease)

Encephalopathy

Encephalitis

• Encephalitis lethargica
• Bickerstaff encephalitis
• Brainstem Encephalitis
• Acute disseminated encephalomyelitis

• NMDR encephalitis (Anti-NMDA receptor)
• VGKC-complex antibody encephalitis which has two subtypes LGI-1 and CASPR2.
• Anti LGI1 encephalitis
• Anti-DPPX Encephalitis
• GABA-A and GABA-B receptors may also be targeted.
• Acute disseminated encephalomyelitis (ADEM)
• Autoimmune basal ganglia encephalitis (BGE)
• Brain-stem encephalitis
  • Opsoclonus-myoclonus syndrome (OMS)
  • Bickerstaff encephalitis
  • Paraneoplastic brainstem encephalitis
  • Rhombencephalitis

• LGI1 encephalitis

Parkinson disease

Parkinson-plus syndromes

• Lewy body dementia
• Progressive supranuclear palsy (PSP)
• Corticobasal syndrome
• Multiple systems atrophy
• UMN: Spasticity + Hyperreflexia

GBS

• Pharyngeal Cervical Brachial (PCB)
• MFS
• Acute ophthalmoparesis without ataxia
• AIDP (Acute inflammatory demyelinating polyradiculoneuropathy)
• Acute motor axonal neuropathy (AMAN) and
• Acute motor-sensory axonal neuropathy (AMSAN)
• Acute panautonomic neuropathy

Wernicke’s encephalopathy

Myasthenia gravis